Practical Considerations In Medical Cannabis Administration And Dosing Pdf

practical considerations in medical cannabis administration and dosing pdf

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Metrics details. With cannabis medicines now obtaining legal status in many international jurisdictions generally on the authorisation of a medical professional , a rapid increase in consumer demand for access to cannabis as a therapeutic option in the treatment and management of a range of indications is being noted. Despite this accessibility, knowledge on optimal use is lacking.

Unfortunately, there is a profound lack of formal veterinary education on the endocannabinoid system ECS and its clinical manipulation, despite its discovery more than 30 years ago. This gap has left practitioners with a lack of knowledge, as well as comfort, in meeting the increasing demands placed on them by clients. In this respect, our human counterparts are decades ahead of us. Physicians that have been practicing cannabinoid medicine for years have accumulated a wealth of anecdotal evidence and experience.

Information for the Veterinary Profession

Skip to search form Skip to main content You are currently offline. Some features of the site may not work correctly. DOI: Russo Published Medicine European journal of internal medicine. Cannabis has been employed medicinally throughout history, but its recent legal prohibition, biochemical complexity and variability, quality control issues, previous dearth of appropriately powered randomised controlled trials, and lack of pertinent education have conspired to leave clinicians in the dark as to how to advise patients pursuing such treatment. View on PubMed.

Javascript is currently disabled in your browser. Several features of this site will not function whilst javascript is disabled. Received 1 August Published 1 December Volume Pages — Review by Single anonymous peer review. Editor who approved publication: Dr Scott Fraser.

*You* Ask the Expert: Interview with Ethan Russo, MD

Marijuana has been touted to have significant therapeutic activity for a wide variety of conditions. Thirty three states currently permit the use of marijuana as a medication through an inconsistent patchwork of regulations. Despite the efforts at the state level to expand the use of marijuana, both as a medicine and for recreational purposes, Cannabis and its constituents remain C-I drugs under the Federal Controlled Substances Act. Recently the U. Food and Drug Administration FDA approved a form of cannabidiol to treat rare but serious pediatric seizure disorders and the U. Over the course of thousands of years, marijuana has been viewed as a component of religious and cultural events, an important medicine, a major agricultural product, and a corrupting national menace.

*You* Ask the Expert: Interview with Ethan Russo, MD

Generally, subjects with terminal illnesses experience significant symptom burden that often increases in intensity over time. In cross-sectional studies, patients report 8—12 symptoms, with fatigue, pain, anorexia, cachexia, dyspnea, anxiety, and depression being particularly common 2 , 3. There are many opportunities to improve palliative care by utilizing both pharmacological and nonpharmacological means. Integration of CBM into palliative care has been delayed by many obstacles, including a paucity of clinical research data, poor clinical knowledge on how to initiate and monitor cannabinoid treatments, and conflicting or confusing regulatory frameworks.

Cannabis has been employed medicinally throughout history, but its recent legal prohibition, biochemical complexity and variability, quality control issues, previous dearth of appropriately powered randomised controlled trials, and lack of pertinent education have conspired to leave clinicians in the dark as to how to advise patients pursuing such treatment. In this article, the authors endeavour to present concise data on cannabis pharmacology related to tetrahydrocannabinol THC , cannabidiol CBD et al. CBD, in contrast to THC, is less potent, and may require much higher doses for its adjunctive benefits on pain, inflammation, and attenuation of THC-associated anxiety and tachycardia. Dose initiation should commence at modest levels, and titration of any cannabis preparation should be undertaken slowly over a period of as much as two weeks. Suggestions are offered on cannabis-drug interactions, patient monitoring, and standards of care, while special cases for cannabis therapeutics are addressed: epilepsy, cancer palliation and primary treatment, chronic pain, use in the elderly, Parkinson disease, paediatrics, with concomitant opioids, and in relation to driving and hazardous activities.

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 Мидж… - Доброй ночи, Чед.  - Она направилась к двери. - Ты уходишь.

 - Это и есть их вес. - Тридцать секунд. - Давайте же, - прошептал Фонтейн.  - Вычитайте, да побыстрее.

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Ethan Russo, MD, is a board-certified neurologist who has been doing research related to cannabinoids for many years.

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CBD, in contrast to THC, is less potent, and may require much higher doses for its adjunctive benefits on pain, inflammation, and attenuation of.

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